Detalhe da pesquisa
1.
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice.
Cell
; 183(4): 1070-1085.e12, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33031744
2.
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.
Nat Immunol
; 18(12): 1299-1309, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28967880
3.
miniMAVS, You Complete Me!
Cell
; 156(4): 629-30, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24529369
4.
Caspase-7 activates ASM to repair gasdermin and perforin pores.
Nature
; 606(7916): 960-967, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35705808
5.
The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.
Proc Natl Acad Sci U S A
; 119(28): e2204511119, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867748
6.
Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway.
J Biol Chem
; 299(1): 102739, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36435197
7.
Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins.
J Virol
; 97(10): e0056323, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37754763
8.
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3.
Bioorg Med Chem Lett
; 99: 129617, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199328
9.
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals.
J Proteome Res
; 22(10): 3159-3177, 2023 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634194
10.
FOXO transcription factors activate alternative major immediate early promoters to induce human cytomegalovirus reactivation.
Proc Natl Acad Sci U S A
; 117(31): 18764-18770, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32694203
11.
A molecular mechanism for probabilistic bet hedging and its role in viral latency.
Proc Natl Acad Sci U S A
; 117(29): 17240-17248, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32632017
12.
Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor.
J Cell Sci
; 133(14)2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32546533
13.
Alternative promoters drive human cytomegalovirus reactivation from latency.
Proc Natl Acad Sci U S A
; 116(35): 17492-17497, 2019 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409717
14.
Two Genetic Differences between Closely Related Zika Virus Strains Determine Pathogenic Outcome in Mice.
J Virol
; 94(20)2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32796074
15.
mTORC2 Activity Disrupts Lysosome Acidification in Systemic Lupus Erythematosus by Impairing Caspase-1 Cleavage of Rab39a.
J Immunol
; 201(2): 371-382, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866702
16.
Structural divergence creates new functional features in alphavirus genomes.
Nucleic Acids Res
; 46(7): 3657-3670, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29361131
17.
An RNA structure-mediated, posttranscriptional model of human α-1-antitrypsin expression.
Proc Natl Acad Sci U S A
; 114(47): E10244-E10253, 2017 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29109288
18.
The Ex Vivo Treatment of Donor T Cells with Cosalane, an HIV Therapeutic and Small-Molecule Antagonist of CC-Chemokine Receptor 7, Separates Acute Graft-versus-Host Disease from Graft-versus-Leukemia Responses in Murine Hematopoietic Stem Cell Transplantation Models.
Biol Blood Marrow Transplant
; 25(6): 1062-1074, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30668984
19.
Inducing circular RNA formation using the CRISPR endoribonuclease Csy4.
RNA
; 23(5): 619-627, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223408
20.
The 5' Untranslated Region of the Major Immediate Early mRNA Is Necessary for Efficient Human Cytomegalovirus Replication.
J Virol
; 92(7)2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29343581